TC1 Square/Cube 1

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Extrachromosomal circular copies of the transposon Tc1.

The 1.6 kb Tc1 transposable element of Caenorhabditis elegans undergoes excision and transposition in the germline. In somatic tissue it is excised at high frequency. Extrachromosomal linear and circular copies of Tc1 have been identified that are likely to be products of somatic and germline excision. In the present study, we have determined the sequences of the sites of circularization in cir...

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Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome.

Trisomy of human chromosome 21 (Hsa21) results in Down syndrome (DS), a disorder that affects many aspects of physiology, including hematopoiesis. DS children have greatly increased rates of acute lymphoblastic leukemia and acute megakaryoblastic leukemia (AMKL); DS newborns present with transient myeloproliferative disorder (TMD), a preleukemic form of AMKL. TMD and DS-AMKL almost always carry...

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A rice Tc1/mariner-like element transposes in yeast.

The Tc1/mariner transposable element superfamily is widely distributed in animal and plant genomes. However, no active plant element has been previously identified. Nearly identical copies of a rice (Oryza sativa) Tc1/mariner element called Osmar5 in the genome suggested potential activity. Previous studies revealed that Osmar5 encoded a protein that bound specifically to its own ends. In this ...

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Arthrobacter aurescens TC1 metabolizes diverse s-triazine ring compounds.

Arthrobacter aurescens strain TC1 was isolated without enrichment by plating atrazine-contaminated soil directly onto atrazine-clearing plates. A. aurescens TC1 grew in liquid medium with atrazine as the sole source of nitrogen, carbon, and energy, consuming up to 3,000 mg of atrazine per liter. A. aurescens TC1 is metabolically diverse and grew on a wider range of s-triazine compounds than any...

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Optimised μMRI for Phenotyping the Tc1 Model of Down Syndrome

brain imaged after 1 week (left) and 5 weeks (right). SNR is visibly improved in the 5 week image, especially in the regions of the cortex and basal ganglia. Figure 1: (Top) Graph showing timecourse of T1 reduction in a central basal ganglia region of interest and the cortex. (Bottom) Example T1 maps from an individual over 5 weeks; (*) map from an individual in our 28-brain study population. F...

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ژورنال

عنوان ژورنال: Wind Engineers, JAWE

سال: 2006

ISSN: 1883-8413,0912-1935

DOI: 10.5359/jawe.2006.621